CEREBRAL BLOOD FLOW FOLLOWING UNILATERAL CAROTID ARTERY OCCLUSION: An Experimental Study

In this study, 26 white New Zealand rabbits weighing between 2-3.5kg were used. Anaesthesia was induced with 1.5glkg urethane intraperitoneally. The ear vein was canulated and an intravenous supply was provided. The femoral artery was catheterized and used to monitor blood pressure. The haemodynamic effects of carotid artery occlusion are not well known. Therefore occluded carotid artery causes some anxiety in various conditions. for example during carotid endarterectomy, and some surgeons prefer to use internal shunt. Some other preventive methods are the measurement of stump pressure and monitoring of cerebral blood flow (CBF)by EEG (11,12). Occlusion of the carotid artery for 15minutes is thought to be well tolerated by patients. and the period might even be lengthened to 30 minutes (1).The results are not known well in longer occlusion than this.